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Analytic epidemiology and periodontal diseases

Identifieur interne : 003D51 ( Main/Exploration ); précédent : 003D50; suivant : 003D52

Analytic epidemiology and periodontal diseases

Auteurs : Brenda Heaton ; Thomas Dietrich

Source :

RBID : ISTEX:B8B17BB5866AFD73B32C036938FD8073D04ED45B

Descripteurs français

English descriptors

Abstract

The validity of epidemiological and clinical observations is paramount, not only for scientific advancement but also in evidence‐based practice. Concern regarding validity with respect to the design and conduct of analytic epidemiological studies is often under‐appreciated, partly as a consequence of our focus on randomized experimental designs as the highest standard of ‘proof’ in clinical science. We review the design, conduct and interpretation of rigorous analytic epidemiological study designs, with specific reference to periodontology. We give special emphasis to intrinsic validity and the use of focused aims to re‐frame the perspective on the strength of evidence in reviews of the literature. Specifically, we draw on the periodontal research literature to provide an overview of the appropriate design and conduct of cohort studies, including randomized designs, case–control and cross‐sectional studies. The concepts of selection bias, information bias and confounding are explored for each study design, both in general terms and with respect to a critical review of the literature on the epidemiology of periodontal diseases.

Url:
DOI: 10.1111/j.1600-0757.2011.00419.x


Affiliations:


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Le document en format XML

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<term>Analytic designs</term>
<term>Analytic epidemiology</term>
<term>Analytic study designs</term>
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<term>Black health study</term>
<term>Case control terminology</term>
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<term>Causal component</term>
<term>Causal contrast</term>
<term>Causal contrasts</term>
<term>Causal effects</term>
<term>Causal inference</term>
<term>Chronic periodontitis</term>
<term>Clin</term>
<term>Clin periodontol</term>
<term>Cohort</term>
<term>Cohort design</term>
<term>Cohort studies</term>
<term>Cohort study</term>
<term>Confounder control</term>
<term>Control group</term>
<term>Control selection</term>
<term>Control studies</term>
<term>Coronary heart disease</term>
<term>Counterfactual</term>
<term>Counterfactual approach</term>
<term>Counterfactual experience</term>
<term>Counterfactual framework</term>
<term>Direct calculation</term>
<term>Disease outcomes</term>
<term>Effect estimate</term>
<term>Effect estimates</term>
<term>Epidemiol</term>
<term>Epidemiological</term>
<term>Epidemiological research</term>
<term>Epidemiological studies</term>
<term>Epidemiology</term>
<term>Exposure assignment mechanism</term>
<term>Exposure distribution</term>
<term>Exposure frequencies</term>
<term>Exposure groups</term>
<term>Exposure information</term>
<term>Exposure levels</term>
<term>Exposure status</term>
<term>Gene polymorphisms</term>
<term>Gingival crevicular</term>
<term>Greenland</term>
<term>Health study</term>
<term>Heaton dietrich</term>
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<term>Metabolic control</term>
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<term>Multiple outcomes</term>
<term>National survey</term>
<term>Natural history</term>
<term>Observational studies</term>
<term>Odds ratio</term>
<term>Oral health</term>
<term>Other designs</term>
<term>Periodontal</term>
<term>Periodontal disease</term>
<term>Periodontal disease etiology</term>
<term>Periodontal disease status</term>
<term>Periodontal diseases</term>
<term>Periodontal literature</term>
<term>Periodontitis</term>
<term>Periodontol</term>
<term>Polymorphism</term>
<term>Possible approaches</term>
<term>Possible bias</term>
<term>Potential outcomes model</term>
<term>Prevalence odds ratio</term>
<term>Prevalent cases</term>
<term>Randomization</term>
<term>Randomized</term>
<term>Randomized studies</term>
<term>Randomized trial</term>
<term>Randomized trials</term>
<term>Rare disease assumption</term>
<term>Rate ratio</term>
<term>Risk ratio</term>
<term>Rothman</term>
<term>Same source population</term>
<term>Selection bias</term>
<term>Sensitivity analysis</term>
<term>Several studies</term>
<term>Single exposure</term>
<term>Source population</term>
<term>Study base</term>
<term>Study baseline</term>
<term>Study conduct</term>
<term>Study design</term>
<term>Study period</term>
<term>Study size</term>
<term>Target population</term>
<term>Temporal sequence</term>
<term>Trohoc fallacy</term>
<term>Unexposed</term>
<term>Unexposed experience</term>
<term>Unexposed individuals</term>
<term>Unexposed subjects</term>
<term>Valid control selection</term>
<term>Valid selection</term>
<term>Validity standpoint</term>
<term>Veterans administration</term>
<term>Wilkins</term>
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<term>Adult periodontitis</term>
<term>Aggressive periodontitis</term>
<term>Analytic approaches</term>
<term>Analytic design</term>
<term>Analytic designs</term>
<term>Analytic epidemiology</term>
<term>Analytic study designs</term>
<term>Assignment mechanism</term>
<term>Bias analysis</term>
<term>Black health study</term>
<term>Case control terminology</term>
<term>Causal</term>
<term>Causal component</term>
<term>Causal contrast</term>
<term>Causal contrasts</term>
<term>Causal effects</term>
<term>Causal inference</term>
<term>Chronic periodontitis</term>
<term>Clin</term>
<term>Clin periodontol</term>
<term>Cohort</term>
<term>Cohort design</term>
<term>Cohort studies</term>
<term>Cohort study</term>
<term>Confounder control</term>
<term>Control group</term>
<term>Control selection</term>
<term>Control studies</term>
<term>Coronary heart disease</term>
<term>Counterfactual</term>
<term>Counterfactual approach</term>
<term>Counterfactual experience</term>
<term>Counterfactual framework</term>
<term>Direct calculation</term>
<term>Disease outcomes</term>
<term>Effect estimate</term>
<term>Effect estimates</term>
<term>Epidemiol</term>
<term>Epidemiological</term>
<term>Epidemiological research</term>
<term>Epidemiological studies</term>
<term>Epidemiology</term>
<term>Exposure assignment mechanism</term>
<term>Exposure distribution</term>
<term>Exposure frequencies</term>
<term>Exposure groups</term>
<term>Exposure information</term>
<term>Exposure levels</term>
<term>Exposure status</term>
<term>Gene polymorphisms</term>
<term>Gingival crevicular</term>
<term>Greenland</term>
<term>Health study</term>
<term>Heaton dietrich</term>
<term>Instrumental variables</term>
<term>Lippincott williams wilkins</term>
<term>Lipponcott williams wilkins</term>
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<term>Metabolic control</term>
<term>Modern epidemiology</term>
<term>Multiple outcomes</term>
<term>National survey</term>
<term>Natural history</term>
<term>Observational studies</term>
<term>Odds ratio</term>
<term>Oral health</term>
<term>Other designs</term>
<term>Periodontal</term>
<term>Periodontal disease</term>
<term>Periodontal disease etiology</term>
<term>Periodontal disease status</term>
<term>Periodontal diseases</term>
<term>Periodontal literature</term>
<term>Periodontitis</term>
<term>Periodontol</term>
<term>Polymorphism</term>
<term>Possible approaches</term>
<term>Possible bias</term>
<term>Potential outcomes model</term>
<term>Prevalence odds ratio</term>
<term>Prevalent cases</term>
<term>Randomization</term>
<term>Randomized</term>
<term>Randomized studies</term>
<term>Randomized trial</term>
<term>Randomized trials</term>
<term>Rare disease assumption</term>
<term>Rate ratio</term>
<term>Risk ratio</term>
<term>Rothman</term>
<term>Same source population</term>
<term>Selection bias</term>
<term>Sensitivity analysis</term>
<term>Several studies</term>
<term>Single exposure</term>
<term>Source population</term>
<term>Study base</term>
<term>Study baseline</term>
<term>Study conduct</term>
<term>Study design</term>
<term>Study period</term>
<term>Study size</term>
<term>Target population</term>
<term>Temporal sequence</term>
<term>Trohoc fallacy</term>
<term>Unexposed</term>
<term>Unexposed experience</term>
<term>Unexposed individuals</term>
<term>Unexposed subjects</term>
<term>Valid control selection</term>
<term>Valid selection</term>
<term>Validity standpoint</term>
<term>Veterans administration</term>
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<front>
<div type="abstract" xml:lang="en">The validity of epidemiological and clinical observations is paramount, not only for scientific advancement but also in evidence‐based practice. Concern regarding validity with respect to the design and conduct of analytic epidemiological studies is often under‐appreciated, partly as a consequence of our focus on randomized experimental designs as the highest standard of ‘proof’ in clinical science. We review the design, conduct and interpretation of rigorous analytic epidemiological study designs, with specific reference to periodontology. We give special emphasis to intrinsic validity and the use of focused aims to re‐frame the perspective on the strength of evidence in reviews of the literature. Specifically, we draw on the periodontal research literature to provide an overview of the appropriate design and conduct of cohort studies, including randomized designs, case–control and cross‐sectional studies. The concepts of selection bias, information bias and confounding are explored for each study design, both in general terms and with respect to a critical review of the literature on the epidemiology of periodontal diseases.</div>
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